Is SARS-CoV-2 Infection a Risk Factor for Early Pregnancy Loss? ACE2 and TMPRSS2 Coexpression and Persistent Replicative Infection in Primitive Trophoblast.

Zhou J, Choi S, Liu H, Zhang J, Tian Y, Edlow AG, Ezashi T, Roberts RM, Ma W, Schust DJ.

J Infect Dis. 2021 Dec 8;224(Suppl 6):S660-S669. doi: 10.1093/infdis/jiab309.

Severe Acute Respiratory Syndrome Coronavirus 2 ACE2 and TMPRSS2 Receptor Protein Expression Patterns Throughout Gestation.

Roberts DJ, Bebell LM, Edlow AG.

J Infect Dis. 2021 Dec 8;224(Supplement_6):S642-S646. doi: 10.1093/infdis/jiab164.

Selective functional antibody transfer into the breastmilk after SARS-CoV-2 infection.

Pullen KM, Atyeo C, Collier AY, Gray KJ, Belfort MB, Lauffenburger DA, Edlow AG, Alter G.

Cell Rep. 2021 Nov 9;37(6):109959. doi: 10.1016/j.celrep.2021.109959. Epub 2021 Oct 22.

COVID-19 mRNA vaccines drive differential antibody Fc-functional profiles in pregnant, lactating, and nonpregnant women.

Atyeo C, DeRiso EA, Davis C, Bordt EA, De Guzman RM, Shook LL, Yonker LM, Fasano A, Akinwunmi B, Lauffenburger DA, Elovitz MA, Gray KJ, Edlow AG, Alter G.

Sci Transl Med. 2021 Oct 27;13(617):eabi8631. doi: 10.1126/scitranslmed.abi8631. Epub 2021 Oct 27.

Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses.

Bordt EA, Shook LL, Atyeo C, Pullen KM, De Guzman RM, Meinsohn MC, Chauvin M, Fischinger S, Yockey LJ, James K, Lima R, Yonker LM, Fasano A, Brigida S, Bebell LM, Roberts DJ, Pépin D, Huh JR, Bilbo SD, Li JZ, Kaimal A, Schust DJ, Gray KJ, Lauffenburger D, Alter G, Edlow AG.

Sci Transl Med. 2021 Oct 27;13(617):eabi7428. doi: 10.1126/scitranslmed.abi7428. Epub 2021 Oct 27.

Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study.

Gray KJ, Bordt EA, Atyeo C, Deriso E, Akinwunmi B, Young N, Baez AM, Shook LL, Cvrk D, James K, De Guzman R, Brigida S, Diouf K, Goldfarb I, Bebell LM, Yonker LM, Fasano A, Rabi SA, Elovitz MA, Alter G, Edlow AG.

Am J Obstet Gynecol. 2021 Sep;225(3):303.e1-303.e17. doi: 10.1016/j.ajog.2021.03.023. Epub 2021 Mar 26.

Vertical transmission of SARS-CoV-2: consider the denominator.

Shook LL, Collier AY, Goldfarb IT, Diouf K, Akinwunmi BO, Young N, Brown A, Hacker MR, Kaimal AJ, Gray KJ, Edlow AG.

Am J Obstet Gynecol MFM. 2021 Jul;3(4):100386. doi: 10.1016/j.ajogmf.2021.100386. Epub 2021 Apr 29.

Multisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier.

Yonker LM, Gilboa T, Ogata AF, Senussi Y, Lazarovits R, Boribong BP, Bartsch YC, Loiselle M, Rivas MN, Porritt RA, Lima R, Davis JP, Farkas EJ, Burns MD, Young N, Mahajan VS, Hajizadeh S, Lopez XIH, Kreuzer J, Morris R, Martinez EE, Han I, Griswold K Jr, Barry NC, Thompson DB, Church G, Edlow AG, Haas W, Pillai S, Arditi M, Alter G, Walt DR, Fasano A.

J Clin Invest. 2021 Jul 15;131(14):e149633. doi: 10.1172/JCI149633.

Imaging Epigenetics of Prenatal THC.

Zürcher NR, Roberts VHJ, Schabel MC, Edlow AG, Hooker JM, Lo JO.

ACS Chem Neurosci. 2021 May 5;12(9):1466-1468. doi: 10.1021/acschemneuro.1c00176. Epub 2021 Apr 14.

COVID-19 mRNA vaccines drive differential Fc-functional profiles in pregnant, lactating, and non-pregnant women.

Atyeo C, DeRiso EA, Davis C, Bordt EA, DeGuzman RM, Shook LL, Yonker LM, Fasano A, Akinwunmi B, Lauffenburger DA, Elovitz MA, Gray KJ, Edlow AG, Alter G.

bioRxiv. 2021 Apr 5:2021.04.04.438404. doi: 10.1101/2021.04.04.438404. Preprint.

Humoral signatures of protective and pathological SARS-CoV-2 infection in children.

Bartsch YC, Wang C, Zohar T, Fischinger S, Atyeo C, Burke JS, Kang J, Edlow AG, Fasano A, Baden LR, Nilles EJ, Woolley AE, Karlson EW, Hopke AR, Irimia D, Fischer ES, Ryan ET, Charles RC, Julg BD, Lauffenburger DA, Yonker LM, Alter G.

Nat Med. 2021 Mar;27(3):454-462. doi: 10.1038/s41591-021-01263-3. Epub 2021 Feb 12.

Sexually dimorphic placental responses to maternal SARS-CoV-2 infection.

Bordt EA, Shook LL, Atyeo C, Pullen KM, De Guzman RM, Meinsohn MC, Chauvin M, Fischinger S, Yockey LJ, James K, Lima R, Yonker LM, Fasano A, Brigida S, Bebell LM, Roberts DJ, Pépin D, Huh JR, Bilbo SD, Li JZ, Kaimal A, Schust D, Gray KJ, Lauffenburger D, Alter G, Edlow AG.

bioRxiv. 2021 Mar 29:2021.03.29.437516. doi: 10.1101/2021.03.29.437516. Preprint.

Umbilical cord blood-derived microglia-like cells to model COVID-19 exposure.

Sheridan SD, Thanos JM, De Guzman RM, McCrea LT, Horng JE, Fu T, Sellgren CM, Perlis RH, Edlow AG.

Transl Psychiatry. 2021 Mar 19;11(1):179. doi: 10.1038/s41398-021-01287-w.

Mismatch between obesogenic intrauterine environment and low-fat postnatal diet may confer offspring metabolic advantage.

Kislal S, Jin W, Maesner C, Edlow AG.

Obes Sci Pract. 2021 Mar 18;7(4):450-461. doi: 10.1002/osp4.501. eCollection 2021 Aug.

Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation.

Matute J, Finander B, Pepin D, Ai X, Smith N, Li J, Edlow A, Villani A, Lerou P, Kalish B.

Res Sq. 2021 Mar 16:rs.3.rs-311000. doi: 10.21203/rs.3.rs-311000/v1. Preprint.

Compromised SARS-CoV-2-specific placental antibody transfer.

Atyeo C, Pullen KM, Bordt EA, Fischinger S, Burke J, Michell A, Slein MD, Loos C, Shook LL, Boatin AA, Yockey LJ, Pepin D, Meinsohn MC, Nguyen NMP, Chauvin M, Roberts D, Goldfarb IT, Matute JD, James KE, Yonker LM, Bebell LM, Kaimal AJ, Gray KJ, Lauffenburger D, Edlow AG, Alter G.

Cell. 2021 Feb 4;184(3):628-642.e10. doi: 10.1016/j.cell.2020.12.027. Epub 2020 Dec 23.

Pediatric Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Clinical Presentation, Infectivity, and Immune Responses.

Yonker LM, Neilan AM, Bartsch Y, Patel AB, Regan J, Arya P, Gootkind E, Park G, Hardcastle M, St John A, Appleman L, Chiu ML, Fialkowski A, De la Flor D, Lima R, Bordt EA, Yockey LJ, D'Avino P, Fischinger S, Shui JE, Lerou PH, Bonventre JV, Yu XG, Ryan ET, Bassett IV, Irimia D, Edlow AG, Alter G, Li JZ, Fasano A.

J Pediatr. 2020 Dec;227:45-52.e5. doi: 10.1016/j.jpeds.2020.08.037. Epub 2020 Aug 20.

Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic.

Edlow AG, Li JZ, Collier AY, Atyeo C, James KE, Boatin AA, Gray KJ, Bordt EA, Shook LL, Yonker LM, Fasano A, Diouf K, Croul N, Devane S, Yockey LJ, Lima R, Shui J, Matute JD, Lerou PH, Akinwunmi BO, Schmidt A, Feldman J, Hauser BM, Caradonna TM, De la Flor D, D'Avino P, Regan J, Corry H, Coxen K, Fajnzylber J, Pepin D, Seaman MS, Barouch DH, Walker BD, Yu XG, Kaimal AJ, Roberts DJ, Alter G.

JAMA Netw Open. 2020 Dec 1;3(12):e2030455. doi: 10.1001/jamanetworkopen.2020.30455.

Protocol-Driven Intensive Outpatient Management of Pregnant Patients With Symptomatic Coronavirus Disease 2019.

Soffer MD, Shook LL, James K, Sawyer MR, Ciaranello A, Mahrouk R, Bernstein SN, Boatin AA, Edlow AG, York-Best C, Kaimal AJ, Goldfarb IT.

Open Forum Infect Dis. 2020 Oct 27;7(11):ofaa524. doi: 10.1093/ofid/ofaa524. eCollection 2020 Nov.

Umbilical cord blood derived microglia-like cells to model COVID-19 exposure.

Sheridan SD, Thanos JM, De Guzman RM, McCrea LT, Horng J, Fu T, Sellgren CM, Perlis RH, Edlow AG.

bioRxiv. 2020 Oct 7:2020.10.07.329748. doi: 10.1101/2020.10.07.329748. Preprint.